عنوان المقالة:تأثير التعرض لدخان السجائر على أنسجة القلب في ذكور الجرذان البيضاء والدور التحسيني لعسل السدر. Effects of exposure cigarette smoke on the cardiac tissues in male albino rats and the improvement role of Sidr honey.
عيدة مفتاح عبدالكريم الشيلابي, نوره ابراهيم الزاعل, وعفاف علي الصالحين
English Authors
Eda M. A. Alshailabi , Nura I. Al-Zail and Afaf A. Alsalhin
Abstract
The aim of this study was to investigate the effects of exposure cigarette smoke on the cardiac tissues in male rats and the improvement role of Sidr honey. Twenty eight male rats were divided into four groups; Group 1: control rats; group 2: rats were given Libyan Sidr honey (100 mg/kg b.w./d.) orally for 4 weeks.; group 3: rats were exposed to the five lit from sidestream of the Karelia red cigarettes (5 times/d.) by a machine smoking for 4 weeks.; and group 4: rats were received the Sidr honey (100 mg/kg b.w./d.) orally for 2 weeks, then the rats were exposed to the Karelia cigarettes generated by a machine smoking with given the Sidr honey for 4 weeks. The X-Ray radiography of rats showing, heart mildly enlarged size in the KC-exposed rats as compared with the NC rats. While, the POR rats showed normal heart size when compared with KC rats. Moreover, the KC group showed a significant increase (P < 0.05) in CK, CK-MB, and LHD as compared to the NC group, whereas the POR group showed a significant decrease (P < 0.05) in the CK, CK-MB, and LHD when compared with the KC group. Histological investigation of the heart tissues of the KC group showed different histopathological changes as compared to the NC group. Nevertheless, the POR group showed the marked improvement in the heart tissues as compared to the KC rats. Conclusion, results demonstrated that Libyan Sidr honey significantly reduced the toxic effects of KC-exposed on the heart structures.
Abstract
The aim of this study was to investigate the effects of exposure cigarette smoke on the cardiac tissues in male rats and the improvement role of Sidr honey. Twenty eight male rats were divided into four groups; Group 1: control rats; group 2: rats were given Libyan Sidr honey (100 mg/kg b.w./d.) orally for 4 weeks.; group 3: rats were exposed to the five lit from sidestream of the Karelia red cigarettes (5 times/d.) by a machine smoking for 4 weeks.; and group 4: rats were received the Sidr honey (100 mg/kg b.w./d.) orally for 2 weeks, then the rats were exposed to the Karelia cigarettes generated by a machine smoking with given the Sidr honey for 4 weeks. The X-Ray radiography of rats showing, heart mildly enlarged size in the KC-exposed rats as compared with the NC rats. While, the POR rats showed normal heart size when compared with KC rats. Moreover, the KC group showed a significant increase (P < 0.05) in CK, CK-MB, and LHD as compared to the NC group, whereas the POR group showed a significant decrease (P < 0.05) in the CK, CK-MB, and LHD when compared with the KC group. Histological investigation of the heart tissues of the KC group showed different histopathological changes as compared to the NC group. Nevertheless, the POR group showed the marked improvement in the heart tissues as compared to the KC rats. Conclusion, results demonstrated that Libyan Sidr honey significantly reduced the toxic effects of KC-exposed on the heart structures.
Publication Date
9/10/2023
Publisher
Bani Waleed University Journal Humanities and Applied Sciences
د. عيدة مفتاح عبدالكريم الشيلابي | Dr. Eda M. A. Alshailabi | 5825