عنوان المقالة:المؤشرات الوراثية للاصابة بمرض الجرب وعلاقتها مع تركيز انترليوكين 12 في الاغنام Genetic parameters for scabies disease and relation with interleukin 12 concentration in sheep
د راسة التاثير الوراثي للاصابة بمرض الجرب لدى الاغنام من خلال ايجاد بعض المعالم الوراثية كالمكافيء الوراثي للاصابة والمعامل التكراري والارتباطات الوراثية بين الاصابة وتركيز الانترليوكين 12 في امصال الحيوانات المصابة ومقارنتها بالسليمة بينها
الملخص الانجليزي
The research carried out to study relationship between scabies with immune response through the level of interleukin 12 (IL-
12) in serum. Moreover, genetic variance for infection and some factors related to animals . Overall mean for incidence rate
was o.70%, age affected by this disease for adults which infected with percentage rate 0.78% among ages 4 - 6 years, whereas
reduced to 0.59% in older animal, however, there are no significant difference with offspring age and lower rate was 0.56% for
lamb less than one year then increased to 0.80% for ages between 1-3 years after that declined to 0.73% for more than 4 years,
there is no impact of sex on infection, on the same side, this study noticed significant differences (P>0.05) between single and
twin were 0.74% and 0.54%, respectively. On the same hand, season has an important role in parasitic incidence, Spring and
Autumn witnessed higher rates reached to 1.00% and 0.75% sequentially, while decreased to 0.53% in winter and 0.50% in
summer. Higher significant response (P>0.05) for IL-12 level for infected received to 0.28ng/ml while reduced to 0.08ng/ml for
healthy animals . Heritability for each of incidence rate of scabies and level of IL-12 were 0.51 and 0.24 respectively whereas
repeatability for this disease was 0.46. There is a high significant correlation between infection and IL-12 concentration was
0.344 and negative (P>0.05) with dam age -0.225 and birth type -0.250 while insignificantly with offspring age reached to
0.147. This research concludes that animal resistance to scabies disease result from interaction between genetic and immune
activation which depended firstly in selecting healthy animals with less incidence of this disease.
انعام عبد الواحد نايف | Inam Abdelwahed Nayyef | 3111