عنوان المقالة:Effect of the Total Lycium barbarum Carotene on Normal Human Blood Lymphocytes Effect of the Total Lycium barbarum Carotene on Normal Human Blood Lymphocytes
احمد رشدي عبد الله | Dr Ahmed Rushdi Abdullah | 2635
نوع النشر
مجلة علمية
المؤلفون بالعربي
AHMED RUSHDI ABDULLAH1 , ZAINAB YASEEN MOHAMMED HASAN2 , KHULOOD.W.ALSAMMARRAIE3
المؤلفون بالإنجليزي
AHMED RUSHDI ABDULLAH1 , ZAINAB YASEEN MOHAMMED HASAN2 , KHULOOD.W.ALSAMMARRAIE3
الملخص العربي
The pioneering and recognition of novel medications, that increase the ability of the immune system tasks has become a very crucial target for the Immune-pharmacology researches as well as for the Onco-therapist. Our scientific work demonstrated the favorable effects of Iraqi wild type Lycium barbarum active components as an immunomodulating agent. The immune stimulating effect of the extracted total carotene notified by the proliferation of the normal blood lymphocytes, which estimated by the MTT assay and the alterations of IL-10 and TNF-α levels that evaluated by ELISA technique. The elevations of those two cytokines have been demonstrated after 2 and 4 hours exposure of the extract at concentrations (125 and 250µg/ml). The results of the present study indicated that Lycium barbarum Carotenoids can behave as an immunostimulant, acted to promote IL-10 production and increase up to four folds TNF-α level especially after 2 hours exposure and at a lower concentration (125µg/ml).
الملخص الانجليزي
The pioneering and recognition of novel medications, that increase the ability of the immune system tasks has become a very crucial target for the Immune-pharmacology researches as well as for the Onco-therapist. Our scientific work demonstrated the favorable effects of Iraqi wild type Lycium barbarum active components as an immunomodulating agent. The immune stimulating effect of the extracted total carotene notified by the proliferation of the normal blood lymphocytes, which estimated by the MTT assay and the alterations of IL-10 and TNF-α levels that evaluated by ELISA technique. The elevations of those two cytokines have been demonstrated after 2 and 4 hours exposure of the extract at concentrations (125 and 250µg/ml). The results of the present study indicated that Lycium barbarum Carotenoids can behave as an immunostimulant, acted to promote IL-10 production and increase up to four folds TNF-α level especially after 2 hours exposure and at a lower concentration (125µg/ml).
تاريخ النشر
30/12/2019
الناشر
International Journal of Pharmaceutical Research
رقم المجلد
11
رقم العدد
1
ISSN/ISBN
0975
رابط DOI
http://www.ijpronline.com/
الصفحات
1087-1093
رابط الملف
تحميل (125 مرات التحميل)
رابط خارجي
http://www.ijpronline.com/
الكلمات المفتاحية
Lycium barbarum carotene, Immunomodulation, IL-10, TNF-α Elisa assay, MTT assay.
رجوع