عنوان المقالة:Effect of the Total Lycium barbarum Carotene on Normal Human Blood Lymphocytes Effect of the Total Lycium barbarum Carotene on Normal Human Blood Lymphocytes
احمد رشدي عبد الله | Dr Ahmed Rushdi Abdullah | 2635
- نوع النشر
- مجلة علمية
- المؤلفون بالعربي
- AHMED RUSHDI ABDULLAH1 , ZAINAB YASEEN MOHAMMED HASAN2 , KHULOOD.W.ALSAMMARRAIE3
- المؤلفون بالإنجليزي
- AHMED RUSHDI ABDULLAH1 , ZAINAB YASEEN MOHAMMED HASAN2 , KHULOOD.W.ALSAMMARRAIE3
- الملخص العربي
- The pioneering and recognition of novel medications, that increase the ability of the immune system tasks has become a very crucial target for the Immune-pharmacology researches as well as for the Onco-therapist. Our scientific work demonstrated the favorable effects of Iraqi wild type Lycium barbarum active components as an immunomodulating agent. The immune stimulating effect of the extracted total carotene notified by the proliferation of the normal blood lymphocytes, which estimated by the MTT assay and the alterations of IL-10 and TNF-α levels that evaluated by ELISA technique. The elevations of those two cytokines have been demonstrated after 2 and 4 hours exposure of the extract at concentrations (125 and 250µg/ml). The results of the present study indicated that Lycium barbarum Carotenoids can behave as an immunostimulant, acted to promote IL-10 production and increase up to four folds TNF-α level especially after 2 hours exposure and at a lower concentration (125µg/ml).
- الملخص الانجليزي
- The pioneering and recognition of novel medications, that increase the ability of the immune system tasks has become a very crucial target for the Immune-pharmacology researches as well as for the Onco-therapist. Our scientific work demonstrated the favorable effects of Iraqi wild type Lycium barbarum active components as an immunomodulating agent. The immune stimulating effect of the extracted total carotene notified by the proliferation of the normal blood lymphocytes, which estimated by the MTT assay and the alterations of IL-10 and TNF-α levels that evaluated by ELISA technique. The elevations of those two cytokines have been demonstrated after 2 and 4 hours exposure of the extract at concentrations (125 and 250µg/ml). The results of the present study indicated that Lycium barbarum Carotenoids can behave as an immunostimulant, acted to promote IL-10 production and increase up to four folds TNF-α level especially after 2 hours exposure and at a lower concentration (125µg/ml).
- تاريخ النشر
- 30/12/2019
- الناشر
- International Journal of Pharmaceutical Research
- رقم المجلد
- 11
- رقم العدد
- 1
- ISSN/ISBN
- 0975
- رابط DOI
- http://www.ijpronline.com/
- الصفحات
- 1087-1093
- رابط الملف
- تحميل (125 مرات التحميل)
- رابط خارجي
- http://www.ijpronline.com/
- الكلمات المفتاحية
- Lycium barbarum carotene, Immunomodulation, IL-10, TNF-α Elisa assay, MTT assay.