عنوان المقالة: The pathogenicity of COVID-19 and the role of pentraxin-3: An updated review study
م.م أمير عذاب عبد الكاظم | Ameer Athab Abulkahim AlAmeri | 3721
نوع النشر
مجلة علمية
المؤلفون بالعربي
المؤلفون بالإنجليزي
Ria Margiana, Satish Kumar Sharma, Bilal Irshad Khan, Ameer A Alameri, Maria Jade Catalan Opulencia, Ali Thaeer Hammid, Thulfeqar Ahmed Hamza, Sharaf Khamrakulovich Babakulov, Walid Kamal Abdelbasset, Zanko Hassan Jawhar
الملخص الانجليزي
In recent years, the COVID-19 pandemic has become one of the most crucial scientific issues in the world, and efforts to eradicate the disease are still ongoing. The acute inflammatory reaction associated with this disease is associated with several complications such as cytokine storm, multiple organ damage, lung fibrosis, and blood clots. PTX3, as part of the humoral innate immune systems, is one of the acute-phase proteins that perform various functions, such as modulating inflammation, repairing tissue, and recruiting immune cells. PTX3 is increased in people with SARS-CoV-2, and its level decreases with proper treatment. Therefore, it can be regarded as a suitable marker for the prognosis of the COVID-19 and evaluating the effectiveness of the treatment method applied. However, some studies have shown that PTX3 can be a double-edged sword and develop tumors by providing an immunosuppressive environment.
تاريخ النشر
15/09/2022
الناشر
Pathology-Research and Practice
رقم المجلد
رقم العدد
رابط DOI
https://doi.org/10.1016/j.prp.2022.154128
رابط خارجي
https://www.sciencedirect.com/science/article/pii/S0344033822003727
الكلمات المفتاحية
COVID-19SARS-CoV-2Pentraxin-3Acute-phase proteins
رجوع