عنوان المقالة:IN VITRO, INTERACTION OF SOME ANTIBIOTICS WITH DIFFERENT FRUIT EXTRACTS ON SOME PATHOGENIC BACTERIAL STRAINS
فريدة ناصر عبد الخالق مصلح | Farida Nasser Mosleh | 4739
- نوع النشر
- مجلة علمية
- المؤلفون بالعربي
- Abboud El Kichaoi, Mahmoud El-Hindi, Farida Mosleh, Ashraf Shafie and *Tarek Elbashiti
- الملخص العربي
- Objective: To evaluate in vitro, the synergistic effects of bioactive extracts of Punica granatum (Pomegranate) "pulp", Actinidia deliciosa (Kiwifruit) "peel" and Citrus maxima (Pomelo) "pulp" with different antibiotics against Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa. Methods: The extraction was carried out using the soxhlet in presence of ethanol, methanol or water. Evaluation of synergistic activity was carried out using disc diffusion method. Results: The results pointed that some of crude extracts showed a synergistic activity against the tested bacteria, and some extract showed no synergistic effect. The highest synergistic effect was observed with streptomycin and ciprofloxancin. Conclusion: Obviously the wide use of antibiotics in the treatment of bacterial infections has led to spread of resistant strains so we need to find a source of bioactive substances that could possess broad spectrum of activity when it is combined with antibiotic to be able resist the pathogenic microorganism.
- تاريخ النشر
- 27/04/2016
- الناشر
- International Journal of Development Research
- رابط الملف
- تحميل (182 مرات التحميل)
- الكلمات المفتاحية
- Synergistic Activity, Fruit Extracts, Disc-diffusion Method, Antibiotics, Pathogenic Bacteria.