عنوان المقالة:تحضیر و تشخیص مركبات الاوكسازبین المشتقة من الاسكوربیك Synthesis And Characterization Of New Oxazepines Derived From D-Erythroascorbic Acid
عبد الجبار عبد القادر مخلص ، منى سمیر الراوي ، جمبد ھرمز توما ، عمار ھاني الدجیلي
المؤلفون بالإنجليزي
A. A. Mukhlus , M. S. Al-Rawi, J. H. Tomma, A. H. Al-Dujaili
الملخص العربي
The new schiff bases derived from D-erythroascorbic acid contaning heterocyclic unit
were synthesized by condensation of D-erythroascorbic acid with aromatic amine (containing 1,3,4-
oxadiazole or 1,3,4-thiadiazole unit) in dry benzene using glacial acetic acid as a catalyst. Derythroascorbic
acid [IV] was synthesized by four steps (Scheme 1), while the primary aromatic amine
which is containing 1,3,4-oxadiazole [VII] or 1,3,4-thiadiazole [VIII] synthesized by the reaction of 4-
methoxy benzoyle hydrazine [VI] with 4-amino benzoic acid or by the reaction tuloic acid with
thiosemicarbazide, respectively in the presence of POCl3. The new 1,3-oxazepine derivatives were
obtained by addition reaction of Schiff bases with different anhydrides in dry benzene,
تاريخ النشر
20/02/2012
الناشر
Ibn Al-Haitham Journal for Pure and Applied Science
منى سمير سعيد | Muna Sameer Saeed AL-rawi | 8891