تم استخلاص اللكتين من عده انواع من الحبوب وتم توصيفها ثم تقدير الفعل التشطيري لللكتينات النباتية .
الملخص الانجليزي
Cucemis melo (C.M) Cucemis sativus (C.S) Citrullus vulgaris (C.V) and Citrullus colocynthus (C.C) seed lectins were separated and partially characterized as biurate positive , have glucose polarity and agglutinate ovine washed 1% erythrocyte suspension The dose determination for these phytolectin mitogenicity were found equal to a mg /50 gm chicks. The white leghorn Giallus domesticus two days old chicks were found as valid animal model for T cell mitogenicity as wing skin test. The C.M, C.S , CN and C.C lectin solutions were found mitogenic in wing skin test model. C.S lectin was the best mitogen among the others. This mitogenicity was of simple positive linear type and it was dose dependent . Refadin and tuberculin were found as immunomodulant of cellular immunosuppressive characters . These, immunomodulating potentials was dose dependent and of simple linear negative type. The developed test system was helpful as an in vivo test for evaluation of T-cell mitogenicity and cellular immunomodulation.
لبنى عبد العظيم مجيد موسى البياتي | Lubna Abdulazeem Al-Bayati | 4727