عنوان المقالة:تحضير، تشخيص طيفي والفعالية البايولوجية لبعض معقدات العناصر الانتقالية المشتقة من { 2,2`((5-methyl-1,3-phenylene)-bis- (oxy))-bis-N`(E`)-2- hydroxybenzylideneacetohydrazide}ligand Preparation, spectral characterization and biological activity of somenewbimetalic complexes derived from{ 2,2`((5-methyl-1,3-phenylene)-bis- (oxy))-bis-N`(E`)-2- hydroxybenzylideneacetohydrazide}ligand
رياض محمود احمد | Riyadh Mahmood Ahmed | 11856
- نوع النشر
- مقال علمي
- المؤلفون بالعربي
- مها يوسف مصطفى و رياض محمود احمد
- المؤلفون بالإنجليزي
- MAHA Y. MUSTAFA* AND RIYADH M. AHMED
- الملخص الانجليزي
- In this work, the preparation of new multidentate Schiff-base lig and and its metal complexes are described. The formation of the lig and{ 2,2`((5-methyl-1,3-phenylene)-bis-(oxy))-bis-N`(E`)-2- hydroxybenzylideneacetohydrazide}[H2L] was prepared from the reaction {2,2-((5-methyl-1,3-phenylene)-bis-(oxy))- di-(acetohydrazide)}[M]precursor and salicylaldehyde in a 1:2 mole ratio, respectively. The reaction of the lig and [H2L] with (Cr+3 , Mn+2 and Fe+2 )metal ions in a 1:2 (L:M) mole ratio. Ligand and complexes were characterised via spectroscopic analyses; [FT-IR, UV-Vis spectroscopy,(C.H.N) microanalysis, chloride content, thermal analysis(TG), electrospray mass, magnetic susceptibility and conductivity measurements. The characterisation data showed the six coordinate complexes with the general formula;[M2(L)Cl4] (where M= Cr+3 ) and K2[M2(L)Cl4] (where M= Mn+2 and Fe+2) .The ligand [H2L] and its complexes were screened for their antimicrobial activity against four bacterial species (Bacillus subtitles and Staphylococcus aureus) G-positive ,(Escherichia coli and Pseudomonas aeruginosa) G-negative and two fungi species(Candida and trichomoniasis). Biological data indicated that complexes become potentially more active against several type of organism, under survey compared with the free lig and.
- تاريخ النشر
- 01/01/2020
- الناشر
- International Journal of Pharmaceutical Research
- رقم المجلد
- 12
- رقم العدد
- 1
- الصفحات
- 238-251
- الكلمات المفتاحية
- multidentate Schiff-base ligand; benzylideneacetohydrazide; spectroscopic analyses;Biological activity.