Objective: Carbon tetrachloride (CCl4) is a highly toxic chemical agent. Therefore, the present study was
carried out to investigate the protective effects of camel's milk against CCL4 induced toxicity in male
rats. Materials and methods: Albino male rats (150-200 g) were divided into four groups of 6 rats: a
control group fed only with diet and tap water for two weeks, the second group fed with standard diet
and camel milk, the third group intoxicated with CCl4 on first two days of the experimental 14 days and
fed with tap water and diet, and the fourth group intoxicated with CCl4 on first two days of the
experimental 14 days and then treated with camel milk. Results: The results indicated that the CCl4
caused a significant increased in the level of serum total cholesterol(TC) , triglycerides(TG), very low
density lipoprotein (VLDL)and low density lipoprotein(LDL), lactate dehydrogenase(LDH), creatine
kinase(CK)and aspartate aminotransferase (AST). Also, there was a significant decreased in the level of
serum high density lipoprotein (HDL).Protective activity of camel's milk against toxicity of CCl4
observed in decreasing of TC, TG, VLDL, LDL, LDH, CK, AST and increased in the HDL levels.
Conclusion: These findings strongly prove that beneficial effects of Camel Milk clearly shown through
the reduction of the CCl4 induced related damages and oxidative stress
علياء ماجد منادي | Alyaa Majid Munadi | 3244