عنوان المقالة: Synethesis, Characterization, and Anticancer Activity Studies of New N-(5-phenyl-1,3,4- oxadiazole-2-yl) propane hydrazide and its Transition Metal Complexes
علياء ماجد منادي | Alyaa Majid Munadi | 3824
نوع النشر
مجلة علمية
المؤلفون بالعربي
المؤلفون بالإنجليزي
LAMYAA A. DAHHAM. IBRAHIM A. FLIFEL, ALYAA MAJID
الملخص الانجليزي
A new ligand of N-(5-phenyl-1,3,4- oxadizole-2-yl) propane hydrazide and its Cu(II), Co(II), and Ni(II) complexes were synthesized. These ligand and its complexes have been characterized by 1HNMR,mass,and Fourier transform infrared (FTIR)spectra, as well as magnetic susceptibility, elemental analysis[C, H, N] and conductance measurements. The program of Hyperchem 7.51 has been used up for theoretical accounts using PM method to study the electrostatic potential that provided good information about the complexity site.Depending to the results obtained we can suggested square planer geometrics for Co(II) and Ni(II) complex, while tetrahedral geometry for Cu(II) complex. In otherwise the ligand and its complexes screened for their anticancer activity. This research showed excellent results in comparison with Ciprofloxacin as standard drug
تاريخ النشر
30/03/2020
الناشر
International Journal of Pharmaceutical Research
رقم المجلد
12
رقم العدد
2
ISSN/ISBN
0975-2366
الصفحات
480-490
رابط الملف
تحميل (56 مرات التحميل)
الكلمات المفتاحية
ligand, complexes, characterization, HyperChem, electrostatic potential, anticancer
رجوع