عنوان المقالة: Synethesis, Characterization, and Anticancer Activity Studies of New N-(5-phenyl-1,3,4- oxadiazole-2-yl) propane hydrazide and its Transition Metal Complexes
A new ligand of N-(5-phenyl-1,3,4- oxadizole-2-yl) propane hydrazide and its Cu(II), Co(II), and Ni(II)
complexes were synthesized. These ligand and its complexes have been characterized by 1HNMR,mass,and
Fourier transform infrared (FTIR)spectra, as well as magnetic susceptibility, elemental analysis[C, H, N] and
conductance measurements. The program of Hyperchem 7.51 has been used up for theoretical accounts using
PM method to study the electrostatic potential that provided good information about the complexity
site.Depending to the results obtained we can suggested square planer geometrics for Co(II) and Ni(II)
complex, while tetrahedral geometry for Cu(II) complex. In otherwise the ligand and its complexes screened
for their anticancer activity. This research showed excellent results in comparison with Ciprofloxacin as
standard drug
علياء ماجد منادي | Alyaa Majid Munadi | 3246