عنوان المقالة:دراسه مستوى TNF-α, IL-4, CCL17 والمؤشر المكروبي للمصابين بالحروق في بابل/العراق Microbial Index and TNF-α, IL-4, CCL17 Level Among Burn Wound Infections in Hilla City, Iraq
أ.م.د.لبنى عبد العظيم البياتي. أ.م.د.حسين الدهموشي. أ.م. جوان احمد
المؤلفون بالإنجليزي
LUBNA ABDULAZEEM1, HUSSEIN O. M. AL-DAHMOSHI2* and JWAN AHMED ALI3
الملخص العربي
٣٠ عينه دم ومصل تم جمعها من المصابين بالحروق والراقدين في ردهه الحروق /مستشفى الحله التعليمي/محافظه/العراق و ٢٠ عينه من الاصحاء كسيطره تم عزل البكتريا وقياس مستويات ال TNF-α, IL-4, CCL17
الملخص الانجليزي
Burn wound infections is the one of the most common nosocomial infections and it is mainly due to bacterial infection. A total of 30 blood and burn swab samples were taken from patients with burn attending Al-Hilla, General Teaching Hospital, in Babylon, Iraq. Twenty blood samples were taken from healthy individual as a control. Conventional bacterial culture were performed to recover bacteria and measurement of TNF-α, IL-4 and CCL17 were performed by ELISA. The results revealed that Pseudomomas aeruginosa were the common agent and compile (76.66%) followed by Escherichia coli and Klebsiella pneumoniae (6.66%) for each and (3.33%) for each of Staphylococcus aureus, Streptococcus pyogenes and Acinetobacter baumannii. Concern the serum levels of TNF-α, IL-4 and CCL17, the results revealed significant decreases of TNF-α level (51.00±16.98 pg/ml) for burn patients in comparison with healthy control (150.70±34.60 pg/ml) p< 0.005. For IL-4 and CCL17 the results displayed non-significant differences between burn patients and healthy control. This study conclude that the Pseudomonas aeruginosa still the main pathogen among burn wound infections and the levels of some cytokines depend upon time of collection and may revealed the worseness degree of burns.
لبنى عبد العظيم مجيد موسى البياتي | Lubna Abdulazeem Al-Bayati | 4712