عنوان المقالة:STUDY OF CHRONIC NEUROTOXICITY BY ACETAMIPRID ® IN RATS STUDY OF CHRONIC NEUROTOXICITY BY ACETAMIPRID ® IN RATS
د. سليم قاسمي | Dr. Salim Gasmi | 23670
نوع النشر
مجلة علمية
المؤلفون بالعربي
قاسمي سليم
المؤلفون بالإنجليزي
Gasmi salim
الملخص العربي
Background: Pollution by pesticides is the main result of technological development in agriculture; Acetamiprid (AC) is a pesticide of the family of new generation organochlorines, so it is controlled by daily doses for short term, but there is a risk in case of chronicity. Aims: The objective of our study is to study biochemical and behavioral neurotoxicity of AC. Methods: In this study, we measured the biomarkers of mitochondrial oxidative stress (GSH, GPx, CAT, SOD, and GST) and brain neurotransmission. Data analysis was performed using Minitab program, a t-test was used to assess the difference between the two groups. Results: The results obtained after administration of AC at 3.14 mg/kg/day of oral weight for 90 days show that AC caused a neurotoxic effect (disruption of neurotransmitter levels). Acetamiprid has an overall pro-oxidative effect;
الملخص الانجليزي
Background: Pollution by pesticides is the main result of technological development in agriculture; Acetamiprid (AC) is a pesticide of the family of new generation organochlorines, so it is controlled by daily doses for short term, but there is a risk in case of chronicity. Aims: The objective of our study is to study biochemical and behavioral neurotoxicity of AC. Methods: In this study, we measured the biomarkers of mitochondrial oxidative stress (GSH, GPx, CAT, SOD, and GST) and brain neurotransmission. Data analysis was performed using Minitab program, a t-test was used to assess the difference between the two groups. Results: The results obtained after administration of AC at 3.14 mg/kg/day of oral weight for 90 days show that AC caused a neurotoxic effect (disruption of neurotransmitter levels). Acetamiprid has an overall pro-oxidative effect;
تاريخ النشر
11/04/2018
الناشر
Journal of biotechnology
رقم المجلد
27
رقم العدد
1
ISSN/ISBN
9567-8786
الصفحات
13
رابط خارجي
https://www.researchgate.net/publication/324018164_STUDY_OF_CHRONIC_NEUROTOXICITY_BY_ACETAMIPRID_R_IN_RATS
الكلمات المفتاحية
Neurotoxicity. Acetamiprid. Pesticides. Rats
رجوع