عنوان المقالة: The Effect of Iron Overload on the Function of Some Endocrine Glands in β-Thalassemia Major Patients.
منال فرحان محسن الخاقاني | Dr. Manal F. Alkhaqani | 3714
نوع النشر
مجلة علمية
المؤلفون بالعربي
المؤلفون بالإنجليزي
HK Al-Hakeim, MM Al-Khaqani
الملخص الانجليزي
Thalassemia is a term that refers to a group of genetic disorders characterized by a defect in the synthesis of hemoglobin. It is sometimes called Mediterranean anemia. Many biochemical changes in the blood accompany this disease. In this research, some biochemical parameters were measured in thalassemic patients and compared with healthy control group. These parameters include Serum iron, TIBC, were measured Spectrophotometrically. Serum ferritin, Iisulin, GH, Testosterone, T3, T4, TSH, Cortisol, & Prolactine were measured by ELISA technique. The results have revealed a moderate state of iron overload in the thalassemia patients. Furthermore, there is a decrease in the level of serum cortisol, T4, prolactine and pancreatic beta cell function percentage (HOMA% B) in thalassemic while serum TSH level is higher in thalassemic patients in comparing with control group. The changes in the hormone levels …
تاريخ النشر
01/02/2013
الناشر
Al-Kufa University Journal for Biology
رقم المجلد
5
رقم العدد
ISSN/ISBN
2
الصفحات
104-123
رابط خارجي
https://www.iasj.net/iasj?func=article&aId=82088
الكلمات المفتاحية
Thalassemia --- Mediterranean anemia --- measured Spectrophotometrically --- Serum ferritin --- Iisulin --- GH --- Testosterone --- T3 --- T4 --- TSH --- Cortisol --- & Prolactine -
رجوع