The study was conducted to determine the temperature change on the growth of marine bacterial isolates of the genus Bacillus isolated from the coastal sediments of Lattakia city. Marine sediment samples were collected from the Apamea region during the period (2019-2020) the identity of these bacterial isolates was determined through laboratory and microbiological analyses. A number of experiments were conducted to find out the effect of temperature changes on the growth of these bacterial isolates. The results showed that the best growth of bacterial isolates was at an incubation temperature of 30°C.