عنوان المقالة:POTENTIOMETRIC STUDY OF RHENIUM(V)COMPLEX FORMATION WITH AZATHIOPRINE AND CEFTRIAXONE POTENTIOMETRIC STUDY OF RHENIUM(V)COMPLEX FORMATION WITH AZATHIOPRINE AND CEFTRIAXONE
جمعه عبدالجواد محمد على | Gomaa A. M. Ali | 20072
نوع النشر
مجلة علمية
المؤلفون بالعربي
Gamal A.H. Gouda, Gomaa A.M. Ali
المؤلفون بالإنجليزي
Gamal A.H. Gouda, Gomaa A.M. Ali
الملخص العربي
The behavior of complex formation of Re(V) metal ion with azathioprine (AZ) and ceftriaxone (CE) as medicinal drugs has been investigated potentiometrically in 0.3 M hydrochloric acid. The stability constant of the prepared complexes has been determined and calculated at various temperatures. The obtained results showed that Re(V)-AZ system showed the formation 1:2, 1:3 and 1:4 complexes, while Re(V)-CE showed only 1:1 and 1:2 complexes. The complex formation suggests a successive displacement of the chloride molecules from the coordination sphere of the central ion by the AZ ligand. In addition, the effect of temperature on the complexes formation of Re(V) with AZ and CE was investigated. The entropy and enthalpy changes showed a favorable and exothermic process, respectively. The kinetic parameters of the formation complex process were calculated and discussed.
الملخص الانجليزي
The behavior of complex formation of Re(V) metal ion with azathioprine (AZ) and ceftriaxone (CE) as medicinal drugs has been investigated potentiometrically in 0.3 M hydrochloric acid. The stability constant of the prepared complexes has been determined and calculated at various temperatures. The obtained results showed that Re(V)-AZ system showed the formation 1:2, 1:3 and 1:4 complexes, while Re(V)-CE showed only 1:1 and 1:2 complexes. The complex formation suggests a successive displacement of the chloride molecules from the coordination sphere of the central ion by the AZ ligand. In addition, the effect of temperature on the complexes formation of Re(V) with AZ and CE was investigated. The entropy and enthalpy changes showed a favorable and exothermic process, respectively. The kinetic parameters of the formation complex process were calculated and discussed.
تاريخ النشر
01/06/2017
الناشر
Malaysian Journal of Analytical Sciences,
رقم المجلد
21
رقم العدد
6
الصفحات
1266-1275
رابط الملف
تحميل (721 مرات التحميل)
رابط خارجي
http://www.ukm.my/mjas/v21_n6/pdf/Gamal_21_6_8.pdf
الكلمات المفتاحية
rhenium(V), drugs, potentiometry, complex formation, stability constant
رجوع