عنوان المقالة:المايكروويف ساعدت في تخليق مشتقات امايد من دواء السبروفلوكساسين وفحص الخواص البايولوجية Microwave assisted synthesis of amide derivatives of the drug ciprofloxacin and screening the biological properties
نادية صادق مجيد | Nadia Sadiq Majeed | 5257
- نوع النشر
- مجلة علمية
- المؤلفون بالعربي
- نادية صادق مجيد , ناظر نجم عبد الله
- المؤلفون بالإنجليزي
- Nadia Sadiq Majeed, Nadhir N. A.Jafar
- الملخص العربي
- It is synthesis of organic compounds derived from drug ciprofloxacin as amide form with the help of microwave irradiation. It created a series of these compounds (3a-3n) by ester derivative as intermediate. These compounds have been diagnosed using the following spectroscopic methods: IR, 1HNMR and 13CNMR as well as the use of elemental microanalysis (CHN) found that all spectra match the look and structural molecule. All compounds proved better effective against bacterial Gram-negative and positive like bacteria type (Proteus mirabilis, Escherichia coli, Staphylococcus aureus, Granuticetella adiacens). Keywords: Antibacterial, Thiazole, Ciprofloxcin, DNA gyrase, fluoroquinolones, Amide.
- الملخص الانجليزي
- It is synthesis of organic compounds derived from drug ciprofloxacin as amide form with the help of microwave irradiation. It created a series of these compounds (3a-3n) by ester derivative as intermediate. These compounds have been diagnosed using the following spectroscopic methods: IR, 1HNMR and 13CNMR as well as the use of elemental microanalysis (CHN) found that all spectra match the look and structural molecule. All compounds proved better effective against bacterial Gram-negative and positive like bacteria type (Proteus mirabilis, Escherichia coli, Staphylococcus aureus, Granuticetella adiacens). Keywords: Antibacterial, Thiazole, Ciprofloxcin, DNA gyrase, fluoroquinolones, Amide.
- تاريخ النشر
- 07/05/2016
- الناشر
- International Journal of ChemTech Research
- رقم المجلد
- رقم العدد
- 7
- ISSN/ISBN
- 2455-9555
- الصفحات
- 387-395
- رابط الملف
- تحميل (147 مرات التحميل)
- الكلمات المفتاحية
- Microwave , Ciprofloxacin