عنوان المقالة:تخليق وتشخيص ودراسة الفعالية البايولوجية لبعض المركبات الحلقية غير المتجانسة الجديدة من مشتق 4- امينو اسيتوفينون SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL ACTIVITY OF SOME NEW HETEROCYCLIC COMPOUNDS DERIVED FROM 4- AMINOACETOPHENONE
نادية صادق مجيد | Nadia Sadiq Majeed | 5255
نوع النشر
مجلة علمية
المؤلفون بالعربي
نادية صادق مجيد , حنان فالح محسن , رضية عبد الباقي
المؤلفون بالإنجليزي
Nadia Sadiq Majeed, Hanan Falah Mohsen and Radhiyah Abdul Baqi
الملخص العربي
Our work aimed for organic synthesis and biological investigation of some new heterocyclic derivatives by three steps : the first step included synthesis of some five-membered and six-membered heterocyclic derivatives (Pyrazole, Isoxazole, Oxazine and Thiazine) from Chalcone. The second step included synthesis of some 1,3-Oxazipene derivatives from Schiff’s bases derived from Azo compound. The third step included the assay of biological activity of all compounds against four types of pathogens bacteria (Staphylococcus aureus, Granutice tella adiacens) gram positive and ( E. coli, Proteus mirabilis) gram negative the results exhibited excellent biological activity for all derivatives compared to antibiotics (Ampicillin and Ciprofloxacin). These compounds were identified and confirmed by FT- IR, 1HNMR, 13CNMR and elemental analysis.
الملخص الانجليزي
Our work aimed for organic synthesis and biological investigation of some new heterocyclic derivatives by three steps : the first step included synthesis of some five-membered and six-membered heterocyclic derivatives (Pyrazole, Isoxazole, Oxazine and Thiazine) from Chalcone. The second step included synthesis of some 1,3-Oxazipene derivatives from Schiff’s bases derived from Azo compound. The third step included the assay of biological activity of all compounds against four types of pathogens bacteria (Staphylococcus aureus, Granutice tella adiacens) gram positive and ( E. coli, Proteus mirabilis) gram negative the results exhibited excellent biological activity for all derivatives compared to antibiotics (Ampicillin and Ciprofloxacin). These compounds were identified and confirmed by FT- IR, 1HNMR, 13CNMR and elemental analysis.
تاريخ النشر
11/05/2018
الناشر
Biochem. Cell. Arch.
رقم المجلد
رقم العدد
ISSN/ISBN
0972-5075
الصفحات
1107-1116
رابط الملف
تحميل (150 مرات التحميل)
الكلمات المفتاحية
Synthesis, heterocyclic derivatives, chalcone, antibacterial
رجوع