عنوان المقالة: A Sensitive Electrochemical Sensor for Rapid Determination of Mebeverine Hydrochloride and Metronidazole Benzoate Selective Molecular Imprinted Polymer in the PVC
إيناس حسن | Inas Hasan | 3357
نوع النشر
مجلة علمية
المؤلفون بالعربي
م.م.إيناس حسن ، أ.د.يحيى كمال البياتي
المؤلفون بالإنجليزي
Inas Al-Khafaji, Yehya Al-Bayati
الملخص الانجليزي
By using precipitation polymerization, liquid electrodes of polymers imprinted with Mebeverine hydrochloride and metronidazole benzoate were created whereas the imprinted polymer (MIP) and non imprinted (NIP) polymers were prepared by using Mebeverine hydrochloride and Metronidazole benzoate qua a template. In the polymerization process, 2-Acrylamido-2-methyl-1-propane Sulphonic acid (AMPS) or 1-Vinylimidazole (VIZ) was used qua monomer, pentaerythritol triacrylate (PETRA) or Divinylbanzene (DVB) was used qua a cross-linker while benzoyl peroxide (BPO) was used as an initiator. The MIP membranes and the membranes of NIP were created by using Dibutyl Sebacate (DBS) and Tris(2-ethylhexyl)phosphate(TEHP) qua plasticizers in PVC matrix. The response time of the liquid electrodes was 1min. whereas their slopes and detection limits reached to 19.62 – 57.36 mV per decade and 1.2 x 10-6 – 2.0 x 10-5 M, respectively. Filling with standard solution of drug (0.1M), the liquid electrodes response -with suitable No.( selectivity for numerous of species - was suitable No.( since pH reached to 1.5 – 12. The developed electrodes were successfully applied for the analyte determination in preparation pharmaceutical sample without any time consuming pretreatment steps.
تاريخ النشر
16/05/2018
الناشر
Ibn Al-Haitham Jour. for Pure & Appl. Sci.
رقم المجلد
31
رقم العدد
1
ISSN/ISBN
2521-3407.
رابط DOI
https://dx.doi.org/10.30526/31.1.1855
الصفحات
75_87
رابط الملف
تحميل (57 مرات التحميل)
رابط خارجي
http://codental.uobaghdad.edu.iq/jih/index.php/j/article/view/1855
الكلمات المفتاحية
molecularly imprinted electrodes, Mebeverine hydrochloride, Metronidazole benzoate, 2-Acrylamido-2-methyl-1-propane sulphonic acid monomer.
رجوع