Toxocariasis, a parasitic infection, carries a major health risk in children, especially in
the developing countries. Children are the most infected group because of their
undeveloped immune system, their higher exposure to infection, and the frequency of
reinfections depending on the factors related to their hygienic and behavioral habits.
Many human infections are asymptomatic, with only eosinophilia and positive serology.
However, several complications were associated with this neglected disease.
These complications depend on the organs invaded by migrating Toxocara larvae, the
degree of the larvae burden, and the strength of the host immune response. This
review aims at giving an update on clinical manifestations, diagnosis, and treatment of
toxocariasis in children. The pediatricians should merge this information into their
clinical diagnosis to defeat this neglected disease by establishing the correct diagnosis
and treatment.