عنوان المقالة:تحضير، تشخيص طيفي والفعالية البايولوجية لبعض معقدات العناصر الانتقالية المشتقة من { 2,2`((5-methyl-1,3-phenylene)-bis- (oxy))-bis-N`(E`)-2- hydroxybenzylideneacetohydrazide}ligand Preparation, spectral characterization and biological activity of somenewbimetalic complexes derived from{ 2,2`((5-methyl-1,3-phenylene)-bis- (oxy))-bis-N`(E`)-2- hydroxybenzylideneacetohydrazide}ligand
رياض محمود احمد | Riyadh Mahmood Ahmed | 12241
نوع النشر
مقال علمي
المؤلفون بالعربي
مها يوسف مصطفى و رياض محمود احمد
المؤلفون بالإنجليزي
MAHA Y. MUSTAFA* AND RIYADH M. AHMED
الملخص الانجليزي
In this work, the preparation of new multidentate Schiff-base lig and and its metal complexes are described. The formation of the lig and{ 2,2`((5-methyl-1,3-phenylene)-bis-(oxy))-bis-N`(E`)-2- hydroxybenzylideneacetohydrazide}[H2L] was prepared from the reaction {2,2-((5-methyl-1,3-phenylene)-bis-(oxy))- di-(acetohydrazide)}[M]precursor and salicylaldehyde in a 1:2 mole ratio, respectively. The reaction of the lig and [H2L] with (Cr+3 , Mn+2 and Fe+2 )metal ions in a 1:2 (L:M) mole ratio. Ligand and complexes were characterised via spectroscopic analyses; [FT-IR, UV-Vis spectroscopy,(C.H.N) microanalysis, chloride content, thermal analysis(TG), electrospray mass, magnetic susceptibility and conductivity measurements. The characterisation data showed the six coordinate complexes with the general formula;[M2(L)Cl4] (where M= Cr+3 ) and K2[M2(L)Cl4] (where M= Mn+2 and Fe+2) .The ligand [H2L] and its complexes were screened for their antimicrobial activity against four bacterial species (Bacillus subtitles and Staphylococcus aureus) G-positive ,(Escherichia coli and Pseudomonas aeruginosa) G-negative and two fungi species(Candida and trichomoniasis). Biological data indicated that complexes become potentially more active against several type of organism, under survey compared with the free lig and.
تاريخ النشر
01/01/2020
الناشر
International Journal of Pharmaceutical Research
رقم المجلد
12
رقم العدد
1
الصفحات
238-251
الكلمات المفتاحية
multidentate Schiff-base ligand; benzylideneacetohydrazide; spectroscopic analyses;Biological activity.
رجوع