عنوان المقالة:New Route for the Synthesis of Pyrazolone Derivatives
د / ممتاز السيد محمد بخيت | Momtaz El-sayed Mohamed Bakheet | 11020
نوع النشر
مجلة علمية
المؤلفون بالعربي
Organic Chemistry - Elixir International Journal
الملخص العربي
An aqueous medium multicomponent synthesis of trans-2-aroyl-5-methyl-3-aryl-3, 5-dihydrofuro [3, 2-c]-quinolin-4(2H)-one in pyridine by conventional and microwave irradiation, easy workup, smaller reaction time and lack of column chromatography are the significant feature of this protocol. The Phenacyl bromide with pyridine is first time used as starting with1-methyl-4-hydroxy quinolone, substituted aromatic aldehydes for the biological interest compound (4a-p) for this green transformation generating one C-O and two C-C bonds in one operation, Knoevenagel followed by Michael addition and intramolecular Cyclisation.
تاريخ النشر
20/12/2015
الناشر
2015
رابط الملف
تحميل (294 مرات التحميل)
الكلمات المفتاحية
Thiosemicarbazide, DMFDMA, Pyrazolone Derivatives, Pyranopyrazole, Arylidene Malononitrile.
رجوع