عنوان المقالة:تأثير عسل السدر على السمية الكبدية في الجرذان المعرضة لدخان السجائر THE EFFECTS OF SIDR HONEY ON HEPATOTOXICITY IN RATS EXPOSED TO SIDESTREAM CIGARETTE SMOKE
عيدة مفتاح عبدالكريم الشيلابي, نوره ابراهيم الزاعل, و وجدان عمران محمد
المؤلفون بالإنجليزي
Eda M. A. Alshailabi, Nura I. Al-Zail, and Wijdan E. Mohammed
الملخص الانجليزي
This work aimed to use Sidr honey (SHY) for the reduction of the acute effects of sidestream
cigarette smoke (SCS) on the liver tissues of rats. 24 rats were divided into 4 groups: (G1)
control group; (G2) rats were administered orally SHY (100 mg/kg BW/30 days; (G3) rats were
exposed to the SCS for a one month, and (G4) rats were taken the SHY 100 mg/kg BW/ 14
days before the rats were exposed to SCS for a one month. The mean AST, ALT, ALP, and
cholesterol values were significantly higher in the G3 than in the G1. In contrast, the G4
showed a significant decline compared to the G3 rats. Moreover, the albumin, total protein,
and HDL levels showed an important reduction in the G3 compared to G1. However, these
parameters improved after treatment with honey in the G4 compared to the G3. Also, the liver
tissue of G4 had some histological changes and a moderate improvement in the tissue's
structure compared to G3. Moreover, the G3 showed the collagen fibers meaningfully
augmented in the central vein wall and portal area, while the G4 presented as nearly similar
to the G1. Therefore, this study confirmed the beneficial effects of SHY in lowering
hepatotoxicity in rats exposed to SCS for one month
تاريخ النشر
01/09/2024
الناشر
MINAR International Journal of Applied Sciences and Technology
ا.د. عيدة مفتاح عبدالكريم الشيلابي | Prof. Dr. Eda M. A. Alshailabi | 6197