عنوان المقالة: Design, Synthesis of Sulfadiazine Derivatives bearing Some New Heterocyclic Compounds with study Antimicrobial and Antioxidant Activity
م.م أمير عذاب عبد الكاظم | Ameer Athab Abulkahim AlAmeri | 3878
نوع النشر
مقال علمي
المؤلفون بالعربي
المؤلفون بالإنجليزي
Hala Shkyair Lihumis, Ameer Alameri, Rawaa Zaooli
الملخص الانجليزي
In this work new heterocyclic derivatives were prepared. The most available (Sulfadiazine) compound treated with different aromatic aldehydes to synthesis (F1-F5) imine derivatives then cycloaddition reaction of imines with phenylthioacetic acid to produced azetidin-2-one derivatives(F6,F7). compound F1 treated ethylene glycol and hydrazine to get (F8) . (F9,F10) compounds has been synthesis by reacting (F1) compound with maleic anhydride and phthalic anhydride in dry benzene . compound F8 treated p-hydroxy benzaldehyde to get (F11) compound. Reaction (F11) with benzoyl chloride gave (F12) compound. Also, (F12) compound treated with urea to get urease derivative .These synthesized compounds (F1-F13) evaluated for their antimicrobial activity and antioxidant activity.
تاريخ النشر
17/05/2022
الناشر
National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT
رقم المجلد
رقم العدد
رابط DOI
10.21608/ejchem.2022.131305.5787
رابط خارجي
https://journals.ekb.eg/article_237833.html
الكلمات المفتاحية
Sulfadiazine; imines; azetidin-2-one; benzaldehyde; antioxidant activity
رجوع