عنوان المقالة:التقذير الطيفي للسيسابرايذ بالاعتماد على تكوين معقذ مسدوج أيوني مع كاشف بروموفينول الازرق Spectrophotometric determination of Cisapride Based on ionpair complex formation with Bromophenol blue
رؤى مؤيد محمود | Ruaa Muayad Mahmood | 9885
نوع النشر
مجلة علمية
المؤلفون بالعربي
أزهار صادق , رؤي مؤيد محمود , سمر احمذ درو شَ خالذة راشذ ع ذُان
الملخص العربي
A new simple, sensitive and inexpensive method has been developed for the spectrophotometric determination of cisapride in pharmaceutical formulation. The turbidimetric method is based on the formation of the ion-pair complex between the drug and bromophenol blue (BPB) in presence of potassium chloride at pH= 2.6, with a maximum absorbance at 520 nm. The calibration graph is linear in the concentration range 5-50μg.ml-1, with good correlation coefficient (r = 0.9989).The limit of detection was found to be 1.14 μg.ml-1 and no interference was observed from common excipients in the pharmaceutical preparation that contain cisapride with good accuracy and precision.
تاريخ النشر
01/10/2010
الناشر
Journal of Kerbala University
رقم المجلد
8
رقم العدد
2
الكلمات المفتاحية
Cisapride, Bromophenol blue
رجوع