عنوان المقالة:الدراسة الحيوية والتشخيص الطيفي وتحضير معقدات قواعد شف غير المتجانسة Metal Complexes of Heterocyclic Hydrazone Schiff-Bases: Preparation, Spectral Characterisation and Biological Study
انعام اسماعيل يوسف, رياض محمود احمد, حسن احمد حس, عيد صالح الفهداوي, محمد جابر الجبوري
المؤلفون بالإنجليزي
Enaam I. Yousif1 • Riyadh M. Ahmed1 • Hasan A. Hasan1 • Aeed S. Al-Fahdawi2 • Mohamad J. Al-Jeboori
الملخص العربي
New isatinic hydrazone Schiff-base ligands,
namely furan-2-carboxylic acid (2-oxo-1,2-dihydro-indol-
3-ylidene)-hydrazide (L1), thiophene-2-carboxylic acid (2-
oxo-1,2-dihydro-indol-3-ylidene)-hydrazide (L2) and
2-(pyridine-2-yl-hydrazono)-1,2-dihydro-indol-3-one) (L3)
are reported. The ligands were prepared by the condensation of furan-2-carboxylic acid hydrazide (L1), thiophene-
2-carboxylic acid hydrazide (L2), and 2-hydrazino pyridine
(L3) with isatine. Monomeric complexes were prepared
from the reaction of the corresponding metal chloride with
the ligands. The ligands and their nine new complexes of
the general formulae [M(Ln)2]Cl2 [where M = Co(II),
Zn(II) and Cd(II); n = L1, L2 and L3] were characterised
by spectroscopic methods (FTIR, UV–Vis, 1H, 13C NMR),
elemental analysis, metal content, magnetic measurement
and molar conductance. These studies revealed the formation of six coordinate complexes, in which the geometry
about metal atom is a distorted octahedral. Biological
activity of the ligands and their metal complexes against
Gram-positive bacterial strain Bacillus (G?) and Gramnegative bacteria Ecoli (G-) are evaluated. The effects of
prepared compounds depend on the type of tested bacteria.
It is clear that the ligands and their metal complexes have a
potential effect on the Gram-positive (G?) and Gramnegative (G-) strains of the tested bacteria.
تاريخ النشر
22/03/2017
الناشر
Iran J Sci Technol Trans Sci
رقم المجلد
رقم العدد
41
رابط DOI
10.1007/s40995-017-0187-z
الصفحات
103-109
الكلمات المفتاحية
Isatinic hydrazone Schiff-bases Heterocyclic compounds Transition metal complexes Spectral and biological study
أ. د. محمد جابر الجبوري | Mohamad J. Al-Jeboori | 5054