ABSTRACT
Background: Acute heart disease patients often go on to develop worsening
renal function, termed as cardiorenal syndrome. The growing breadth of studies
has shown the implications of combining multiple biomarkers to better chart
outcomes between heart and kidneys, and produce desirable results in such
patients, as tryptase. Aim of the study: To estimate the levels of tryptase, and
their relationship with cardiorenal syndrome. Methods: Tryptase were obtained
from 62 samples: 40 sample with cardiorenal syndrome, and 22 normal healthy.
Results: A highly significant increase (p<0.0001) in the levels of tryptase in
serum of patients with cardiorenal syndrome, heart disease and kidney disease
compared with normal individuals. Conclusions: Tryptase has higher diagnostic
validity values in the current study, which may be useful as a diagnostic tool to
identify recurrence of the cardiorenal syndromes.
تاريخ النشر
09/12/2015
الناشر
International Journal of Medical Research Professionals