عنوان المقالة: Studies on bacteriological and biochemical tests of urinary tract infections in some Iraqi patients undergoing hemodialysis due to renal failure and chronic kidney diseases
Abstract:
Background: Quantification of proteinuria and urine creatinine concentration are important in kidney failure and chronic kidney diseases (C K D) assessment. In most kidney diseases, urine contains large amounts of protein and there are good correlations between the urine protein to creatinine ratios and the 24 hour urine. Some patients with renal failure and chronic kidney diseases suffered from bacterial infections.
Objective: The aims of this study are to investigate the protein; creatinine ratio in some Iraqi patients with kidney failure and chronic kidney diseases. Also, to detect the bacterial infections in CKD.
Methods : the relationship between protein and creatinine in urine samples was done in (70) patients (35 female and 35 male) with kidney failure and chronic kidney diseases, aged from (18 – 65) years, at a period from September 2016 –December 2017 at AL-Yarmuk Hospital Teaching / Baghdad. The urine volume and total protein measuring in 24 hr. samples were evaluated. The susceptibility of identified species of pathogenic bacteria to many antibiotics were tested.
Results: From the data, the elderly age between (39 - 65) had (50 %) kidney failure and chronic kidney disease. The urine total proteins in females were (56.8%) and in males (43.1%). On the other hands, the urine creatinine in females were (62.5%) but in males were (37.5%). The protein / creatinine ratios in females were (56.25%) and in males were (43.75%). The highest protein / creatinine ratio was detected in male with age (65) years old, and the total protein of this patient was (2.4 g/24 hr) and urine creatinine was (0.6 mg/kg/day), so the protein / creatinine ratio was 4g protein per19 creatinine. (61.42%) cases showed no growth upon culture, whereas (38.57%) cases were found to have significant bacterial growth in patients with KFD. The numbers of E. coli and CONS isolates in females were higher than in males, whereas S. aureus and Klebsiella spp. isolates in males were higher than in females with KDF.
Conclusions: The proteins / creatinine ratio on a 24 hr. urine samples give evidence to existence of significant proteinuria. It is a quick and accurate method to estimate proteinuria excretion and give an indication of renal failure and CKD in Iraqi patients.
د. تغريد خضر محمد | Dr.Taghreed Khudhur Mohammed | 5326