Objective: The acute coronary syndromes [unstable angina (UA) and acute myocardial infarction (AMI)] are more dangerous than others ischemic heart diseases (IHD) due to acute morphological changes in atherosclerotic plaques which cause (acute ischemia) severe imbalance between myocardium demand and oxygen supply. The present study was designed to determine and compare the levels of (GOT, GPT, Total protein , Albumin ,Globulin and Uric acid) in patients with (ACS) and healthy individuals. Material and Methods: serum glutamate oxaloacetate transaminase (S.GOT) , serum glutamate pyruvate transaminase (S.GPT) , serum total protein , serum albumin , serum globulin and serum uric acid levels were measured in 75 subjects which were divided into three groups : (25) patients of UA and (25) patients of AMI , were compared with (25) healthy subjects (control).Results:The levels of serum glutamate oxaloactate transaminase(S.GOT) , serum glutamate pyruvate transaminase(S.GPT), serum albumin and serum uric acid were significant increase in patients of (UA) and (AMI) when compared with control. Whereas the levels of serum albumin showed a significant decrease in patients of (UA) in comparison with control group , whereas its levels was not affected in blood serum of (AMI) patients in comparison with control. While the levels of serum globulin showed significant increase in patients of AMI in comparison with control group, whereas its levels was not affected in blood serum of (UA) patients in comparison with control (p≤0.01).Conclusion: High levels of GOT , GPT , globulin and low levels of total protein and albumin could be causative for ACS.
تاريخ النشر
30/01/2014
الناشر
International Journal of Scientific & Engineering Research
م.د. هديل رشيد فرج | Dr.Hadeel Rashid Faraj | 4096