A facile and cost effective chemical reduction method is employed for the preparation of reduced
graphene oxide/hydroxyapatite (rGO/HAp) nanocomposites. The transmission electron microscopy
images revealed that the HAp flakes are well decorated on the surface of rGO. The morphological
structure of the as-synthesized rGO/HAp nanocomposites was confirmed through X-ray diffraction,
Fourier transform infrared spectroscopy and Raman spectroscopy, while the composition and thermal
stability were analyzed by energy dispersive spectra and thermogravimetric analysis, respectively.
Furthermore, the effect of rGO/HAp nanocomposites for the proliferation of Human Mesenchymal Stem
Cell (hMSC) was performed to confirm the biocompatibility. A selective chemical sensor based on rGO/
HAp modified glassy carbon electrode (GCE) for sensitive detection of Bis-phenol A (BPA) has been
developed. Several important parameters controlling the performance of the BPA chemi-sensor were
investigated and optimized at room conditions. The rGO/HAp/Nafion/GCE sensor offers a fast response
and highly sensitive BPA detection. Under the optimal conditions, a linear range from 0.2 nmol L1 to
2.0 mmol L1 for the detection of BPA was observed with the detection limit of 60.0 pmol L1 (signal-tonoise ratio, at an SNR of 3) and sensitivity of 18.98 104mA.L/mmol.m2
. Meanwhile, the fabricated
chemi-sensor showed an excellent, specific and selective recognition to target BPA molecules among
coexistence of other analytes in the buffer system. This novel effort initiated a well-organized way of
efficient rGO/HAp/Nafion/GCE sensor development and practically analyzed the real hazardous
environmental pollutants at room conditions.
د. امير على الزواوى | Dr. Amir Aly Elzwawy | 2114