عنوان المقالة:Khairy M. A. Zoheir, Ahmed, R.G., 2012. Patterns of folliculogenesis in ducks following the administration of a gonadotropin-releasing hormone 1 (GnRH) analogue. J. of Genetic Engineering & Biotechnology. 10, 93–99.
The efficacy of synthetic gonadotrophin-releasing hormone (GnRH) analogue in
improving the folliculogenesis of ducks has not been established. The aim of the study was to investigate
the effect of oral administration of GnRH analogue as luteinizing hormone releasing hormone
A2 (LHRH-A2) on expression of relevant genes, egg production, changes of hormone
levels and an ovarian follicle development in ducks. Five hundred ducks at 220 days old were randomly
allotted to five groups, where each bird received daily in food 0, 5, 10, 15, or 20 lg LHRH-A2
for 60 days. In all treated groups, a non-significant increase in the level of GnRH receptor was
noticed as compared to the corresponding control. Interestingly, the egg product in the 10 and
15 lg LHRH-A2 groups was profoundly increased (P < 0.05) if compared to 0 and 5 lg LHRHA2
groups or control. A reduction in circulating prolactin (PRL) levels occurs concurrently with
an increase in progesterone (P4) and estradiol (E2) particularly in 5, 10 and 15 lg LHRH-A2 groups.
Maximal apoptotic percentage for the granulosa cells was obtained in 20 lg LHRH-A2 group as
compared to control or 5, 10 and 15 lg treatment groups. Finally, these data suggest that the oral
administration of 10 and 15 lg LHRH-A2 may induce ovarian cycle and play vital gonadotrope role during the folliculogenesis process in ducks. This study also demonstrated a need to concentrate
further research on the potential effect of GnRH during the early period to improve the reproductive
performance.
Ahmed R. G. | Ahmed R. G. | 2259