عنوان المقالة: Serum Neutrophil Gelatinase-Associated Lipocalin and Cystatin C are early Biomarkers of Contrast-Induced Nephropathy after Coronary Angiography in Patients with Chronic Kidney Disease
د. صباح محمد الحرازي | Sabah Mohamed Alharazy | 3076
- نوع النشر
- مجلة علمية
- المؤلفون بالعربي
- المؤلفون بالإنجليزي
- Sabah Mohamed Alharazy, Norella Kong, Rashidi Saidin, Abdul Halim Abdul Gafor, Oteh Maskon, Marlyn Mohd and Syed Zulkifli Syed Zakaria
- الملخص العربي
- Angiology. 2014 May; 65(5):436-42. Doi: . PMID: 23580616 [PubMed - indexed for MEDLINE].
- الملخص الانجليزي
- We had previously reported on serum neutrophil gelatinase-associated lipocalin (NGAL) as an earlier biomarker of contrast-induced nephropathy (CIN) than serum creatinine (SCr) in 100 patients with chronic kidney disease undergoing coronary angiography.1 We then compared serum NGAL to serum cystatin C (CysC) in the same group of patients. The SCr, estimated glomerular filtration rate, serum NGAL, and serum CysC were measured at baseline and various time points as appropriate post-procedure. The frequency of CIN was 11% (n = 11). Serum NGAL increased ≥25% from baseline at 24 hours in 7 patients with CIN (P = .04). Serum CysC increased ≥25% from baseline at 24 hours in 4 patients with CIN (P = .008). Changes in serum NGAL and serum CysC from baseline at 24 hours (▵ values) could diagnose CIN 24 hours earlier than SCr with serum NGAL showing a superior performance.
- تاريخ النشر
- 01/05/2014
- الناشر
- SAGE Journals-Angiology
- رقم المجلد
- 65
- رقم العدد
- 5
- رابط DOI
- 10.1177/0003319713483918
- رابط الملف
- تحميل (89 مرات التحميل)
- رابط خارجي
- https://journals.sagepub.com/doi/abs/10.1177/0003319713483918
- الكلمات المفتاحية
- neutrophil gelatinase-associated lipocalin, cystatin C, contrast-induced nephropathy, coronary angiography, chronic kidney disease