عنوان المقالة:The Impact of Serum Manganese, Molybdenum and Selenium Levels on Pathogenesis of Preeclampsia The Impact of Serum Manganese, Molybdenum and Selenium Levels on Pathogenesis of Preeclampsia
محمد عباس حسن | Mohammed Abbas Hasan | 7495
نوع النشر
مجلة علمية
المؤلفون بالعربي
Nadia Mudher Al-Hilli, Haydar Hashim Al-Shalah, and Mohammed Abbas Hasan.
المؤلفون بالإنجليزي
Nadia Mudher Al-Hilli, Haydar Hashim Al-Shalah, and Mohammed Abbas Hasan.
الملخص العربي
Preeclampsia is a disease that is peculiar to pregnancy, It affect women after twenty weeks of gestation and resolve completely after peurperium. In this study we tried to find any association of changes in serum levels of trace and ultra-trace elements manganese, molybdenum, and selenium with the development of pre-eclampsia. The study included 120 women, half of them (60) were diagnosed as preeclamptic in the third trimester while the other sixty were healthy pregnant women (controls) in the last trimester. Measurement of serum levels of these substances was done using graphite furnace atomic absorption spectrophotometer technique. The results were expressed as mean ± standard error of mean. Statistically significance is defined at a P value < 0.05. Serum Manganese and selenium levels were significantly lower in patients with pre-eclampsia compared to control groups, (7.617 ± 0.293μg/dl vs. 10.847 ± 0.356μg/dl) and (2.546 ± 0.068μg/dl vs. 4.306 ± 0.050μg/dl), (P. value <0.05) respectively. while molybdenum level was not significantly different (2.304 ± 0.173 μg/dl vs. 2.670 ± 0.172 μg/dl), (P. value ˃ 0.05). As conclusion, Deficient levels of manganese and selenium could have a role in the pathogenesis of PE.
الملخص الانجليزي
Preeclampsia is a disease that is peculiar to pregnancy, It affect women after twenty weeks of gestation and resolve completely after peurperium. In this study we tried to find any association of changes in serum levels of trace and ultra-trace elements manganese, molybdenum, and selenium with the development of pre-eclampsia. The study included 120 women, half of them (60) were diagnosed as preeclamptic in the third trimester while the other sixty were healthy pregnant women (controls) in the last trimester. Measurement of serum levels of these substances was done using graphite furnace atomic absorption spectrophotometer technique. The results were expressed as mean ± standard error of mean. Statistically significance is defined at a P value < 0.05. Serum Manganese and selenium levels were significantly lower in patients with pre-eclampsia compared to control groups, (7.617 ± 0.293μg/dl vs. 10.847 ± 0.356μg/dl) and (2.546 ± 0.068μg/dl vs. 4.306 ± 0.050μg/dl), (P. value <0.05) respectively. while molybdenum level was not significantly different (2.304 ± 0.173 μg/dl vs. 2.670 ± 0.172 μg/dl), (P. value ˃ 0.05). As conclusion, Deficient levels of manganese and selenium could have a role in the pathogenesis of PE.
تاريخ النشر
06/12/2016
الناشر
Research Journal of Pharmaceutical, Biological and Chemical Sciences
رقم المجلد
8
رقم العدد
1
ISSN/ISBN
0975-8585
الصفحات
7
رابط الملف
تحميل (438 مرات التحميل)
رابط خارجي
https://www.researchgate.net/publication/312990650_The_Impact_of_Serum_Manganese_Molybdenum_and_Selenium_Levels_on_Pathogenesis_of_Preeclampsia
الكلمات المفتاحية
Pre-eclampsia, Manganese, Molybdenum, Selenium, Graphite Furnace Atomic Absorption Spstrophotometry
رجوع