عنوان المقالة: Implications of Extracellular Vesicles in Blood Protozoan Parasitic Diseases
ا.د. نجوى مصطفى السيد | Nagwa Mostafa El-Sayed | 3515
- نوع النشر
- فصل في كتاب
- المؤلفون بالعربي
- نغم جمال مسعود . نجوى مصطفى السيد . منار عز العرب رمضان
- المؤلفون بالإنجليزي
- Nagham Gamal Masoud, Nagwa Mostafa El-Sayed , Manar Ezz Elarab Ramadan
- الملخص الانجليزي
- Blood protozoan parasites are single-cell organisms that can be found in the bloodstream of the infected individuals or spread to others through exposure to infected blood as in blood transfusion. The medically important blood protozoa are Plasmodium spp., Leishmania spp., and Trypanosoma spp. Infection by these parasites is naturally transmitted by insects (vectors). They cause life-threatening diseases that are among the most widespread and lethal all over the world with high prevalence in developing countries. Research studies showed that extracellular vesicles (EVs) released from these blood protozoa or infected host cells play a significant role in the pathogenesis of parasitic diseases and have an effective role on the host immune responses. Blood protozoa–released EVs transfer genetic materials among parasites and different cells in the host leading to the dissemination of parasitic infections. More importantly, EVs provide a new direction in the management of blood protozoan parasitic diseases as well as may be candidates for immune prevention of these parasitic diseases. This chapter summarizes the implications of extracellular vesicles in blood protozoan parasitic diseases, mainly focusing on trypanosomiasis, leishmaniasis, and malaria.
- تاريخ النشر
- 01/01/2021
- الناشر
- Springer
- رقم المجلد
- رقم العدد
- ISSN/ISBN
- 978-981-15-6599-1
- رابط DOI
- doi.org/10.1007/978-981-15-6599-1_12
- الصفحات
- 261-276
- رابط خارجي
- https://link.springer.com/chapter/10.1007/978-981-15-6599-1_12
- الكلمات المفتاحية
- Plasmodium spp., Leishmania spp., Trypanosoma spp., Extracellular vesicles, Pathogenesis