Jabbar S. Hassan , Reyam F. Salah , Ayad M. Gaidan
الملخص الانجليزي
Background: Chlamydia trachomatis is an obligate intracellular bacterium most commonly associated with sexually transmitted diseases. In females, infection with this bacterium is well-documented as a cause of infertility. However, in males this effect is controversial. The aim of current study was to investigate the association of C. trachomatis infection in infertile male genital tract with some sperm parameters. Method: This is a case-control study including 100 seminal fluid specimens from infertile men and other 100 specimens from fertile men as controls. Specimens from both groups were subjected for macroscopic and microscopic examinations. Bacterial DNA was extracted from each sample and 16S ribosomal gene of C. trachomatis was amplified with specific primers using conventional polymerase chain reaction (PCR). Results: Seventeen specimens from infertile men were positive for C. trachomatis DNA versus one specimen from fertile men. A comparison of sperm quality between C. trachomatis-positive and –negative infertile men revealed a significant association between the presence of C. trachomatis in male genital tract and low sperms concentration and motility. Conclusion: This study provided further evidence indicating that the motility and morphology of sperm are significantly influenced by the presence of C. trachomatis in male genital tract.
تاريخ النشر
12/12/2019
الناشر
R.K. Sharma, Institute of Medico-Legal Publications
جبار سلمان حسان | Jabbar Salman Hassan | 774