عنوان المقالة:
مصعب نورالدين محمد حمد | Mosab Nouraldein Mohammed Hamad | 4486
نوع النشر
مقال علمي
المؤلفون بالعربي
مصعب نورالدين محمد حمد
المؤلفون بالإنجليزي
Mosab Nouraldein Mohammed Hamad
الملخص الانجليزي
Myecetoma is one of the neglected tropical diseases, most prevalent in tropical and subtropical regions in the area known as myecetoma belt. It is caused either by fungi (eumycetes) or bacteria (actinomycetes). We suggest that, through their strong and stable, mycotoxin inhibits pain and aryl hydrocarbon receptor actions and promotes IL-17 release. Furthermore, it affects Catechol-O-methyltransferase (COMT), which is responsible for male sexual orientation and this explains the predominance of myecetoma among men and we suggest that the size of lesion is related to the strength of COMT activity in male patients. Due to the absence of laboratory facilities, we are not able to achieve more than these suggestions, so experimental studies are recommended.
تاريخ النشر
09/04/2022
الناشر
Researchgate
رقم المجلد
3
رقم العدد
2
رابط DOI
http://dx.doi.org/10.36346/sarjm.2022.v03i02.001
رابط خارجي
https://www.researchgate.net/publication/359846585_The_Role_of_Mycotoxin_in_Myecetoma_Pathogenesis
الكلمات المفتاحية
Myecetoma, Mycotoxin, Pain receptors, Aryl hydrocarbon receptor, IL-17, Catechol-O-methyltransferase
رجوع