-أريد

نوع النشر: مقال علمي
المؤلفون بالعربي
المؤلفون بالإنجليزي: Amal Amin, Moshera Samy, Sameh Hosam Abd El-Alim, Abd El Gawad Rabia & Magdy M. H. Ayoub
الملخص الانجليزي: Vitamin C (Vit.C)-entrapped polycaprolactone (PCL) nanoparticles (Vit.C–PCNs) were prepared by encapsulation of Vit.C into PCL-based nanoparticles (PCNs) which were prepared using double emulsion method with two steps. First, the inner aqueous phase (W1) was added to dichloromethane solution containing PCL with homogenization to form primary emulsion (W1/O) which was emulsified with the outer aqueous phase (W2) containing polyvinyl alcohol as stabilizer to attain the double emulsion (W1/O/ W2). Versatile parameters were investigated to reach to the most successful formulation for Vit.C–PCNs, such as time, effect of speed of homogenization on drug encapsulation efficiency, etc.
تاريخ النشر: 07/02/2018
الناشر: International Journal of Polymeric Materials and Polymeric Biomaterials
رقم المجلد
رقم العدد: 67
ISSN/ISBN: 0091-4037
رابط DOI: 10.1080/00914037.2017.1393816
الصفحات: 942-950
رابط الملف: تحميل (0 مرات التحميل)
رابط خارجي: https://www.tandfonline.com/doi/abs/10.1080/00914037.2017.1393816
الكلمات المفتاحية: Biopolymers; drug carriers; drug delivery; encapsulation; nanoparticles; polycaprolactone; vitamin C