عنوان المقالة: مراجعة : معقدات قواعد شف مع بعض االمواد الدوائية Review: Schiff base complexes of some drug substances
ا.د. لقاء خالد عبد الكريم | lekaa khalid abd al-karem | 21355
- Publication Type
- Journal
- Arabic Authors
- لقاء خالد عبد الكريم وفوزي وداي و نسرين حسين كرم
- English Authors
- Lekaa K.Abdul Karem , Dr.Fawzi Y.Waddai Dr.Nisreen H. Karam
- Abstract
- Schiff bases (SBs) represent multipurpose ligands that can be prepared from the concentration of prime amines with carbonyl clusters. Creation of SB transition metal compounds via as ligands has opportunity of attaining coordination complexes of abnormal arrangement and stability. These transition metal compounds have extraordinary attention as a consequence of their dynamic portion in metalloenzymes and as biomimetic prototypical complexes as a result of their proximity to usual enzymes and proteins. These complexes are imperative in medicinal disciplines owing to their widespread range of biological actions. They mostly exhibit organic actions involving antifungal, antibacterial, antitumor, antidiabetic, herbicidal, antiproliferative, anticancer, and anti-inflammatory actions. The organic action of transition metal compounds resulting from the Schiff base ligands was extensively investigated. This paper reviews the scope, significance, and antimicrobial actions of Schiff base metal compounds.
- Abstract
- Schiff bases (SBs) represent multipurpose ligands that can be prepared from the concentration of prime amines with carbonyl clusters. Creation of SB transition metal compounds via as ligands has opportunity of attaining coordination complexes of abnormal arrangement and stability. These transition metal compounds have extraordinary attention as a consequence of their dynamic portion in metalloenzymes and as biomimetic prototypical complexes as a result of their proximity to usual enzymes and proteins. These complexes are imperative in medicinal disciplines owing to their widespread range of biological actions. They mostly exhibit organic actions involving antifungal, antibacterial, antitumor, antidiabetic, herbicidal, antiproliferative, anticancer, and anti-inflammatory actions. The organic action of transition metal compounds resulting from the Schiff base ligands was extensively investigated. This paper reviews the scope, significance, and antimicrobial actions of Schiff base metal compounds.
- Publication Date
- 8/5/2019
- Publisher
- Journal of Pharmaceutical Sciences and Research
- Volume No
- 11
- Issue No
- 1
- File Link
- تحميل (726 مرات التحميل)
- Keywords
- Synthesis, Spectroscopic , Biological Studies