عنوان المقالة:تحضير وتشخيص وفعالية بايولوجية لمعقدات الفلزات لقواعد شف الحلقية Metal Complexes of Heterocyclic Hydrazone Schiff-Bases: Preparation, Spectral Characterisation and Biological Study
رياض محمود احمد/ انعام اسماعيل يوسف/ حسن احمد حسن/ محمد جابر الجبوري
English Authors
Riyadh M. Ahmed, Enaam I. Yousif, Hasan A. Hasan, and Mohamad J. Al-Jeboori
Abstract
A new macrocyclic multidentate Schiff-base ligand Na4L consisting of two submacrocyclic units (10,21-bis-iminomethyl-3,6,14,17-
tricyclo[17.3.1.18,12]tetracosa-1(23),2,6,8,10,12(24),13,17,19,21,-decaene-23,24-disodium) and its tetranuclear metal complexes with
Mn(II), Co(II), Ni(II), Cu(II), and Zn(II) are reported. Na4L was prepared via a template approach, which is based on
the condensation reaction of sodium 2,4,6-triformyl phenolate with ethylenediamine in mole ratios of 2 : 3. The tetranuclear
macrocyclic-based complexes were prepared from the reaction of the corresponding metal chloride with the ligand. The mode
of bonding and overall geometry of the compounds were determined through physicochemical and spectroscopic methods. These
studies revealed tetrahedral geometries about Mn, Co, and Zn atoms. However, square planar geometries have been suggested
for NiII and CuII complexes. Biological activity of the ligand and its metal complexes against Gram positive bacterial strain
Staphylococcus aureus and Gram negative bacteria Escherichia coli revealed that the metal complexes become more potentially
resistive to the microbial activities as compared to the free ligand. However, thesemetal complexes do not exhibit any effects on the
activity of Pseudomonas aeruginosa bacteria.There is therefore no inhibition zone.
رياض محمود احمد | Riyadh Mahmood Ahmed | 12018