عنوان المقالة:تحضير ، أطياف، خواص وفعالية بايولوجية لليكاند قاعدة شيف ومعقدات الفاز لبعض الأملاح الفلزية الثنائية مع حامض الأنثرانيلك. Synthesis, Spectroscopic, Characterization and Biological Activities of Schiff Base Ligand and Metal Complexes of Some Metal (II) Salts with Anthranilic Acid.
أ.م.شذى محمد حسن ، م.فائزة حسن غانم و أ.د.عباس علي صالح الحمداني.
English Authors
Shatha M H Obaid, Faeza Hasan Ghanim, and Abbas Ali Salih Al-Hamdani
Abstract
Schiff base N,N'-Bis-(4-dimethylamino-benzylidene)-benzene-1,4-diamine has been synthesized from 4-dimethylaminobenzenaldehyde and benzene-1,4-diamine. The structure of Schiff base was obtained by (C.H.N.) microanalysis, Mass, 1HNMR, FT-IR and UV-Vis spectral methods and thermal analysis. Metal mixed ligand complexes of some metal(II) salts with Schiff base ligand and anthranilic acid were prepared in the molar ratio (1:2:2), (Metal):(SBL)2:(Anthra)2, (SBL)= Schiff base ligand, (Anthra) =anthranilic acid and Metal= Co(II), Ni(II), Cu(II), Zn(II), Cd(II) and Hg(II). The thermal behaviour (TGA) of the complexes was studied. The prepared complexes identified by using mass, thermal analysis, FT.IR and UV-Vis spectrum methods, on otherwise flame atomic absorption, magnetic properties and conductivity measurements. According, the characterization of the complexes from the mixture of anthranilic acid and the ligand prepared according to Schiff base ligand exhibited that the anthranilic acid make the coordination with metals (II) without existence of the Schiff base ligand. The coordination became Metal:(Anthra)2, from The physico-chemical data suggested octahedral geometry for the all complexes. The Schiff base ligand, anthranilic acid and metal(II)- complexes were screened for antibacterial activity against Staphlococcus epidermidies and Staphylococcus aureus (Gram Positive Bacteria) as well as Klebsiella and Escherichia coli (Gram Nagetive Bacteria) by the agar well diffusion method.
Publication Date
12/1/2019
Publisher
Research Journal of Pharmaceutical, Biological and Chemical Sciences
Volume No
10
Issue No
1
Pages
1121-1131
Keywords
Anthranillic acid; transition metal complexes; mass spectra; thermal analysis and Bacteria-activities
شذى محمد حسن عبيد | Shatha Mohammed Hassan Obaid | 10950