Batool ali khorsheed1 , Sawsan M. Jabbar AL-Hasnawi2 , Ali Nayyef Assi3
Abstract
BACKGROUND: Gallstones are one of the most prevalent digestive disorders. Helicobacter pylori (H. pylori) are a human pathogen
affecting over 50% of the world population. Helicobacter pylori has a role in upper gastrointestinal disorders, including gallstones. So
this study aimed to detect the association of H. pylori with gallstones, therefore developing apossible a preventative strategy for
gallstone formations by modification type of treatment.
METHOD: current study was conducted on 95 patients referred to the surgical clinic of Al-Husain General Hospital, Al Nasiriyah,
Real-Time PCR technique was performed for in detection of Helicobacter pylori based on amplification UreC gene in gall bladder
samples after cholecystectomy.
RESULTS: Out of the 95 patient’s 31(33%) were positive for H. pylori UreC gene.
CONCLUSION: The presence of H. pylori in gallbladder mucosa might indicate a big risk for cholelithiasis. Real time PCR is a rapid
reliable method for the detection of H. pylori DNA in gallbladder. This rapid molecular approach could help clinicians to effectively
manage patients at high risk of developing gallstones at an earlier stage.
Publication Date
10/5/2019
Publisher
International Journal of Medical Science and Current Research (IJMSCR)
سوسن محمد جبار الحسناوي | Sawsan M. Jabbar AL-Hasnawi | 3321