عنوان المقالة:تأثير الفينفاليرات على بعض معايير الدم الفسيولوجية والكيميائية الحيوية والهرمونية في ذكور الجرذان Effect of fenvalerate on some physiological, biochemical and hormonal blood criteria in male rats
In this study (120) adult male rats were used. The animals were divided into four groups, three of these groups were the experiment groups that treated with different doses of the fenvalerate (10.125, 21.25, and 42.5 mg/kg) of rats for three time periods were 10 days and 20 day and 30 days and the last group was the control group that gave distilled water. The criteria that have been studied: Blood parameter such as the number of the RBCs and WBCs count, the level of hemoglobin, the packed cells volume (hematocrit) and platelet counts. and biochemical parameter which included glucose, cholesterol, albumin and liver function test ALT and AST and FSH, LH and testosterone hormones and sperm parameter such as the total sperm count and sperm abnormality. The results from hematological parameter indicated significant decrease in all hematological parameter except WBCs count and biochemical parameter showed significant increase in liver function test ALT and AST, glucose, cholesterol and cearatinin and significant decrease in albumin, follicle-stimulating hormone(FSH), luteinizing hormone(LH) and Testosterone hormone. Significant decrease in the total sperm count and live sperm.
Publication Date
1/1/2016
Publisher
Research Journal of Pharmaceutical, Biological and Chemical Sciences
أ.د. علاء الدين صبحي محسن السلامي | Professor.Dr. Alaauldeen S.M.ALSallami | 8210