Saad Sabbar Dahham, Mohamad Taleb Agha, Yasser M Tabana, Amin Malik Shah Abdul Majid
Abstract
Banana is one of the oldest fruit crops domesticated by humans, delicious test and nutritional value
has made it one of the most economically important plants in the globe. In this work, banana peels and pulps
were extracted with two organic solvents as well as water. Six extracts were tested for antioxidant properties
using two methods (2, 2’-diphenyl-1-picrylhydrazyl radical (DPPH) and ferric reducing antioxidant power
(FRAP) assays). They were also screened for antiangiogenic activity using the rat aorta ring assay as well as
antineoplasic activity using MTT assay. The correlation between antiangiogenic and antioxidant activities also
was evaluated. Of the six extracts tested, 2 exhibited significant antiangiogenic activity. The hexane extracts of
banana peels had the highest activity (85.32% inhibition at 100 µg/mL. Similarly, the hexane extract of banana
peel had the highest cytotoxic activity and was found to inhibit the growth of colon cancer cell line HCT-116.
سعد صبار دحام | Saad Sabbar Dahham | 8287