عنوان المقالة:تقدير بعض العناصر النادرة والحالة المضادة للأكسدة في مرضى سرطان الثدي الذين يخضعون للعلاج الإشعاعي Estimation of Some Trace Elements and Antioxidant Status in Breast Cancer Patients Undergoing Radiotherapy
عبدالرحمن رشيد محمود، محمد رعد عبدالله، حسام سليم خلف
English Authors
Abdulrahman R. Mahmood , Mohamad R. Abdullah, Husam S. Khalaf
Abstract
Breast cancer (BC) is the most prevalent tract cancer in the world, including Iraq. The classified breast
tumors to benign, malignant, and radiotherapy. Cancer treatment depends on certain stages such as
mastectomy then chemotherapy alone or with radiation therapy or endocrine therapy according to the
prognostic features obtained from the pathology report. The present study included 100 females. The
women were split into two groups, control group that consisted of 50 apparently healthy females and 50
patients with BC group who undergo the radiotherapy. The current study highlighted on some of the
anthropometric measurements, including the oxidative stress index malondialdehyde (MDA), the
concentrations of total antioxidant capacity (TAC), serum albumin (Alb), serum uric acid (UA), and
finally the concentrations of copper (Cu) and zinc (Zn) as trace elements were measured as well. The
results were compared to control. There was a significant variation in MDA and albumin when
comparing patient group with control, while uric acid was statistically insignificant when comparing
control group with patients group. Cu concentration was statistically high when compared with control
group. On the other side, a significant decrease of Zn concentration of patients was observed
compared to control group .In this study, the evaluation of these parameters maybe used as a helpful tool
in treatment of breast cancer.
حسام سليم خلف | Husam S. Khalaf | 5157