عنوان المقالة:تحضير مركب نانوي مضاد للفطريات من كرايسوفلافين و اوكسيد الزنك وتحديد الفعالية التثبيطية ضد العزلات الفطرية الجلدية Preparation of a Nanohybrid Antifungal from Griseovulvin and Zinc Oxide and Determination of Inhibitory Activity against Dermatophyte Isolates
زهراء شاكر محمد : بلقيس عبد علي عبد عون جواد : نورس الخفاجي
English Authors
Z. S. Mahmo1, B. A. A. Jwad and N. M. Al-Khafaji
Abstract
In the current study Gri-ZnO,a new nanohybrid antifungal, was prepared using Sol-Gel ion exchange between the antifungal griseovulvin (Gri) and zinc oxide. Gri-ZnO was confirmed by changes in the FT-IR and x-ray spectrums, compared with zinc oxide. New nanodimensions were also observed in atomic force microscopy. The antifungal activity of free griseovulvin and Gri-ZnO was studied against 12 patient
dermatophytes belonging to three species, Trichophyton mentagrophytes, Epidermophyton floccosum and Microsporum canis. While some of
the isolates showed resistance to both Gri and Gri-ZnO others were susceptible, with average inhibition zone sup to15 mm.
بلقيس عبد علي عبد عون | Balkeas Abd Ali Abd Aun | 7127