Objective: To asses the protective effect of phenolic extract of cyperus rotundus
rhizomes on biochemical in isoproterenol induced myocardial infraction. Methods: Myocardial
infarction was induced in rats by intraperitoneally injection of isoproterenol (85mg/kg) for two
consecutive days at an interval of 24 h. Rats were treated with phenolic extract of cyperus
rotundus rhizomes at two doses (15mg/kg, 30 mg/kg) for period 21 days and isoproterenol was
injected on the 21 th and 22 th day. At the end of experiment i.e. on the 23 th day biochemical
changes were monitored from control and experimental groups. Results: ISO injected rats
showed a significant increase in d-dimer levels. In addition, it also exhibited alteration in the
levels of electrolytes (Na+ and Cl-). It also showed significant decrease in level of K+.
Pretreatment with phenolic extract of cyperus rotundus rhizomes significantly prevented the
ISO induced alteration in biochemical changes. Conclusions: The present result shows that
treatment with phenolic extract of cyperus rotundus rhizomes in ISO injected rats significantly
attenuates induced myocardial infarction.
Publication Date
12/17/2018
Publisher
International Conference on Materials Engineering and Science
علياء ماجد منادي | Alyaa Majid Munadi | 3768