AL-DAFAEE, MOHAMMED ESSA; JASIM, ANAM AZIZ; MOHAMMED, TAGHREED KHUDHUR; MOHAMMED, RABAB QASIM; NAbdullah, HANAA; HARHOOSH, MUATAZ ADNAN
Abstract
Background: Viral Hepatitis C (HCV) is a contagious disease that mainly effects on the liver. HCV is not
associated with any symptoms, whereas the chronic infection may lead to necrosis of the liver, and after
years cirrhosis may appear. Cirrhosis patients suffer from liver cancer, or very swollen veins in the organs
of digestive system, which can lead to severe bleeding and death. HBV causes acute and chronic hepatitis.
Some people experience vomiting, yellowing, fatigue, dark urine and abdominal pain. The means of
transmission of the virus is by direct exposure to the infected blood or body fluids and intravenous (IV)
drug use are the common methods of infection, working in health care centers, blood banks, dialysis,
contact with infected patients, travel to countries with a high incidence of the disease and via Tattoos.
Objective: To determine the seroprevalence of HCV and HBsAg in blood donors attended to the National
Center for Blood Transfusion / Virus Unit in Baghdad.
Methods: The study was done in a period from January 2019 to December 2019. 190,773 venous blood
samples were taken from blood donors attended to The National Center for Blood Transfusion/ in Baghdad
city. Serum samples were tested for viral markers by enzyme-linked immunosorbent assay technique
(ELISA), HBsAg ELISA Kit to detect the hepatitis B surface antigen (HBsAg), anti– HCV ELISA Kit
(Fortress HCV kit). To confirm viral hepatitis infection VIDAS Anti-HCV panel system to detect HCV
infection.
Results: The results showed positive records for Hepatitis B and C types, which were 476 (0.24%) for
HBV and 188 (0.098%) for HCV out of total 190773 of blood donors. it is observed that the highest
percentage of infection with HBV was in May; it was 51 out of 14280(0.35%). While, the highest
percentage of infection with HCV was in June; it was 20 out of 15690(0.12%). The percentage of males
with HBV and HCV were 0.25% and 0.095% respectively. In females, the percentages were 0.095% (3 out
of 3157) and 0.28 % (9 out of 3157) for HBV and HCV respectively.
Conclusion: the percentages of infection of HCV and HBV in blood donors are relatively high, and early
detection of viruses is very important before blood transfusion.
Keywords. Hepatitis, HBV, HCV, Blood Donor, Baghdad.
معتز عدنان حرحوش العبيدي | Muataz adnan Harhoosh | 4087