عنوان المقالة:Surfactant-Assisted Co-Precipitation Synthesis of Ca-Doped Ceria Nanoparticles for Antibacterial Applications Surfactant-Assisted Co-Precipitation Synthesis of Ca-Doped Ceria Nanoparticles for Antibacterial Applications
Ibrahim A. Amar, Shamsi A. Shamsi, Ruqayah M. Saheem, Amdallah A. Altawati, Mohammed A. Abdulkarim, Mabroukah A. Abdulqadir, Ihssin A. Abdalsamed
English Authors
Ibrahim A. Amar, Shamsi A. Shamsi, Ruqayah M. Saheem, Amdallah A. Altawati, Mohammed A. Abdulkarim, Mabroukah A. Abdulqadir, Ihssin A. Abdalsamed
Abstract
Antibiotic-resistant pathogenic bacteria (e.g., multi-drug resistant bacteria, MDR) have been one of the major threats to human health. Nanoparticles, the newly emerging tools, hold the promise to solve the antibiotic resistance-related problems. This study aimed at evaluating the antibacterial activities of Ca-doped ceria nanoparticles (CDC) against the Gram-negative bacteria (Pseudomonas aeruginosa and Klebsiella pneumoniae) and Gram-positive bacteria (Staphylococcus aureus) using optical density measurement. Co-precipitation method was used to synthesize the Ca-doped ceria nanoparticles with and without addition of cetyltrimethylammonium bromide (CTAB, cationic surfactant). The prepared nanoparticles were characterized using the X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), and UV-Vis spectroscopy. The XRD results demonstrated that, the CDC-CTAB nanoparticles (synthesized via CTAB-assisted co-precipitation method) had the smaller crystallite size (16.26 nm) and higher specific surface area (56.72 m2/g) compared to the CTAB-free synthesized sample (CDC nanoparticles). In addition, the CDC-CTAB nanoparticles exhibited a better inhibition percentage of bacteria growth (29.54-34.08%) against both the Gram-negative and Gram-positive bacteria. In terms of materials cost and toxicity, Ca-doped ceria nanoparticles can be considered as promising materials and, their biological activity might be evaluated against other microorganisms.
إبراهيم علي أحمد عمار | Ibrahim Ali Ahmed Amar | 15312