Throughout this study, multi-drug resistant P. aeruginosa was isolated from neonatal infections in order to detect
the genes being responsible of antibiotic resistance in these bacteria by molecular technique (PCR). Antibiotic sensitivity
test results demonstrated that P. aeruginosa have (100%) resistance against each Carbenicillin, Amoxyclave, Cephalothin
and Rifampicin, and high level resistance ≥70% for most other antibiotics. While 0% resistance (100% sensitivity) was
shown against each IPM, MRP. The results of minimum inhibitory concentration,MIC, by using HiComb test showed that
P. aeruginosa has 100% resistance for Amoxyclave (4-240µg/ml), 70% for Cloramphenicol(4-120 µg/ml), 60% for
Cefepem(16-128 µg/ml), 50% for Ciprofloxacin(0.5-120 µg/ml), 30% for Amikacin(0.032-128 µg/ml), 20% for
Piperacillin(5-120 µg/ml) and 10% for Ceftazidime(8-64 µg/ml). PCR results demonstrated that among 35 isolates of
P. aeruginosa, highest incidence 51.4% have arr-2 gene followed by 49% have aac(3)I and 37% have blaCARB.
Publication Date
10/5/2014
Publisher
International Journal of Medicine and Pharmaceutical Sciences (IJMPS)
أ.د. أمل طالب عطيه السعدي | Prof. Dr. Amal Talib Atiyah Al Sa'ady | 6335