عنوان المقالة:تقييم الديناميكيا الخاصة بتدفق الدم للخصية عقب حقن هرمون الجونادوتروبين بمساعدة الاشعة التلفيزيونية (نبض موجة دوبلر) في الكباش وعلاقتها بالاستجابة الهرمونية Evaluation of testicular hemodynamics following gonadotropin-releasing hormone administration with the aid of pulse wave Doppler in rams and their relation to hormonal response
محمد سعداوي راوي - جابر أحمد مجاهد - عبد الباسط إ. عبد الباسط - أحمد سعد أحمد حسانين
English Authors
Mohammed Rawy; Gaber Megahed; Abdelbaset Abdelbaset; Ahmed Hassaneen
Abstract
The vascularization of the testis through testicular artery is of great importance to maintain its
normal function. The vascular disruption due to inadequate arterial blood flow of the testis
negatively affects testicular function and semen quality. This study aimed to determine the efficacy
of gonadotropin-releasing hormone (GnRH) administration on testicular vascularity in relation to
testosterone hormonal response. Five clinically healthy adult ossimi rams 18- to 30-months-old
were used. Testicular arteries Doppler examination, blood sampling following GnRH
administration and testosterone hormonal assay were conducted. Both pulsatility index (PI) and
resistance index (RI) significantly decreased in all treated rams starting from 1 hr till 120 hrs after
single GnRH administration, both Doppler indices returned to their pre-treatment values at 144
hours after GnRH administration. Doppler peak systolic velocity (PSV) did not change in response
to GnRH administration. Testosterone hormone concentrations negatively correlated with PI and
RI but not PSV. In conclusion, GnRH would be useful a beneficial therapy for the treatment of
testicular dysfunction in rams by increasing testosterone concentrations and testicular blood flow.
And pulse wave Doppler ultrasonography would be a useful non-invasive clinical tool for
evaluation of the efficacy of novel therapeutic treatments in rams.
أحمد سعد أحمد حسانين | Ahmed Saad Ahmed Hassaneen | 6069