Abstract:
The present study is conducted to prepare Ibuprofen as polymeric prodrug to improve its important physiochemical properties, increasing water solubility
and decrease its side-effects. The product is characterize by using chemical and spectral methods.Then controlled release of Ibuprofen in from its polymer, in different phosphate buffers ( pH =8.5,7.5 and 1).The result show the
percentage release of Ibuprofen was high at basic pH.
د. لقاء عبدالرضا رحيم الربيعي | dr. Leaqaa A.R.Al-Rubaie | 5221